Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance

Herausgegeben:Igaz, Peter

Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance

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Beschreibung

MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body fluids, most notably in blood. Significant differences of circulating microRNA levels have been found in various diseases, making them candidates for minimally invasive markers of disease, for example tumor malignancy. The book focuses on the potential diagnostic applicability of circulating microRNAs in various diseases and their potential biological significance.

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Details

ISBN978-3-0348-0953-5

ProduktartBuch

EinbandartGebunden

Verlag/Label

Springer

Erscheinungsdatum02.12.2015

ReiheExperientia Supplementum

Reihen-Nr.106

Seiten288 Seiten

SpracheEnglisch

Weitere Details

Reihe

DNA Fingerprinting: State of the Science

Control Problems in Industry

Comparative Physiology of the Heart: Current Trends

Molecular, Clinical and Environmental Toxicology - Molecular, Clinical and Environmental Toxicology

Environmental Toxicology

Galanin

Matrix Metalloproteinase Inhibitors

T Lymphocytes as Tools in Diagnostics and Immunotoxicology

Fluorescent Methods for Molecular Motors

Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance

AMP-activated Protein Kinase

Inflammasomes: Clinical and Therapeutic Implications

Metabolic Interaction in Infection

Nanomedicine

Genetics of Endocrine Diseases and Syndromes

Antibody Glycosylation

Interaction of Immune and Cancer Cells

Microsporidia

Autor:in

Herausgegeben:Igaz, Peter

Peter Igaz has degrees in medicine and molecular biology. He works as an associate professor in medicine at Semmelweis University Budapest. He is very actively involved in research focusing on the genomics and bioinformatics of endocrine tumors; the study of microRNAs forms a special focus of his research. His research group was among the first to describe tissue microRNA profiles and microRNA biomarkers of malignancy in adrenocortical and adrenomedullary tumors, and circulating microRNAs in adrenocortical tumor patients. His group developed a novel microRNA target prediction algorithm and analyzed pathways involved in adrenal tumors with bioinformatics tools.